Glycopeptides as versatile tools for glycobiology

被引:141
作者
Buskas, Therese [1 ]
Ingale, Sampat [1 ]
Boons, Geert-Jan [1 ]
机构
[1] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA
关键词
glycobiology; glycopeptides; glycoproteins; oligosaccharide; synthesis;
D O I
10.1093/glycob/cwj125
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review describes the recent advances in the field of glycopeptide and small glycoprotein synthesis. The strategies covered include chemical and chemoenzymatic synthesis, native chemical ligation (NCL), and expressed chemical ligation. The importance of glycopeptide synthesis is exemplified by giving the reader an overview of how versatile and important these well-defined glycopeptides are as tools in glycobiology.
引用
收藏
页码:113R / 136R
页数:24
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