Environmental biocatalysis: from remediation with enzymes to novel green processes

被引:258
作者
Alcalde, Miguel [1 ]
Ferrer, Manuel [1 ]
Plou, Francisco J. [1 ]
Ballesteros, Antonio [1 ]
机构
[1] CSIC, Dept Biocatalisis, Inst Catalisis & Petroleoquim, E-28049 Madrid, Spain
关键词
D O I
10.1016/j.tibtech.2006.04.002
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Modern biocatalysis is developing new and precise tools to improve a wide range of production processes, which reduce energy and raw material consumption and generate less waste and toxic side-products. Biocatalysis is also achieving new advances in environmental fields, from enzymatic bioremediation to the synthesis of renewable and clean energies and biochemical cleaning of 'dirty' fossil fuels. Despite the obvious benefits of biocatalysis, the major hurdles hindering the exploitation of the repertoire of enzymatic processes are, in many cases, the high production costs and the low yields obtained. This article will discuss these issues, pinpointing specific new advances in recombinant DNA techniques amenable to future biocatalyst development, in addition to drawing the attention of the biotechnology community to the active pursuit and development of environmental biocatalysis, from remediation with enzymes to novel green processes.
引用
收藏
页码:281 / 287
页数:7
相关论文
共 58 条
[11]   Biocatalysts for clean industrial products and processes [J].
Bull, AT ;
Bunch, AW ;
Robinson, GK .
CURRENT OPINION IN MICROBIOLOGY, 1999, 2 (03) :246-251
[12]   Functional expression of a fungal laccase in Saccharomyces cerevisiae by directed evolution [J].
Bulter, T ;
Alcalde, M ;
Sieber, V ;
Meinhold, P ;
Schlachtbauer, C ;
Arnold, FH .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2003, 69 (02) :987-995
[13]   Lignin-derived compounds as efficient laccase mediators for decolorization of different types of recalcitrant dyes [J].
Camarero, S ;
Ibarra, D ;
Martínez, MJ ;
Martínez, AT .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2005, 71 (04) :1775-1784
[14]   Immobilised enzymes: science or art? [J].
Cao, LQ .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2005, 9 (02) :217-226
[15]   Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design [J].
Chica, RA ;
Doucet, N ;
Pelletier, JN .
CURRENT OPINION IN BIOTECHNOLOGY, 2005, 16 (04) :378-384
[16]   Bacterial cell surface display of organophosphorus hydrolase for selective screening of improved hydrolysis of organophosphate nerve agents [J].
Cho, CMH ;
Mulchandani, A ;
Chen, W .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2002, 68 (04) :2026-2030
[17]   Metagenomic gene discovery: past, present and future [J].
Cowan, D ;
Meyer, Q ;
Stafford, W ;
Muyanga, S ;
Cameron, R ;
Wittwer, P .
TRENDS IN BIOTECHNOLOGY, 2005, 23 (06) :321-329
[18]   Is bioaugmentation a feasible strategy for pollutant removal and site remediation? [J].
El Fantroussi, S ;
Agathos, SN .
CURRENT OPINION IN MICROBIOLOGY, 2005, 8 (03) :268-275
[19]   Mining genomes and 'metagenomes' for novel catalysts [J].
Ferrer, M ;
Martínez-Abarca, F ;
Golyshin, PN .
CURRENT OPINION IN BIOTECHNOLOGY, 2005, 16 (06) :588-593
[20]   Containment of a genetically engineered microorganism during a field bioremediation application [J].
Ford, CZ ;
Sayler, GS ;
Burlage, RS .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1999, 51 (03) :397-400