Brain activation modulated by sentence comprehension

被引:798
作者
Just, MA
Carpenter, PA
Keller, TA
Eddy, WF
Thulborn, KR
机构
[1] CARNEGIE MELLON UNIV,DEPT STAT,PITTSBURGH,PA 15213
[2] UNIV PITTSBURGH,MED CTR,DEPT RADIOL,PITTSBURGH,PA 15213
关键词
D O I
10.1126/science.274.5284.114
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The comprehension of visually presented sentences produces brain activation that increases with the linguistic complexity of the sentence. The volume of neural tissue activated (number of voxels) during sentence comprehension was measured with echo-planar functional magnetic resonance imaging. The modulation of the volume of activation by sentence complexity was observed In a network of lour areas: the classical left-hemisphere language areas (the left laterosuperior temporal cortex, or Wernicke's area, and the left inferior frontal gyrus, or Broca's area) and their homologous right-hemisphere areas, although the right areas had much smaller volumes of activation than did the left areas. These findings generally indicate that the amount of neural activity that a given cognitive process engenders is dependent on the computational demand that the task imposes.
引用
收藏
页码:114 / 116
页数:3
相关论文
共 26 条
[1]   Neural systems engaged by planning: A PET study of the Tower of London task [J].
Baker, SC ;
Rogers, RD ;
Owen, AM ;
Frith, CD ;
Dolan, RJ ;
Frackowiak, RSJ ;
Robbins, TW .
NEUROPSYCHOLOGIA, 1996, 34 (06) :515-526
[2]   TIME COURSE EPI OF HUMAN BRAIN-FUNCTION DURING TASK ACTIVATION [J].
BANDETTINI, PA ;
WONG, EC ;
HINKS, RS ;
TIKOFSKY, RS ;
HYDE, JS .
MAGNETIC RESONANCE IN MEDICINE, 1992, 25 (02) :390-397
[3]   FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF HUMAN AUDITORY-CORTEX [J].
BINDER, JR ;
RAO, SM ;
HAMMEKE, TA ;
YETKIN, FZ ;
JESMANOWICZ, A ;
BANDETTINI, PA ;
WONG, EC ;
ESTKOWSKI, LD ;
GOLDSTEIN, MD ;
HAUGHTON, VM ;
HYDE, JS .
ANNALS OF NEUROLOGY, 1994, 35 (06) :662-672
[4]   THE ROLE OF THE RIGHT-HEMISPHERE IN THE INTERPRETATION OF FIGURATIVE ASPECTS OF LANGUAGE - A POSITRON EMISSION TOMOGRAPHY ACTIVATION STUDY [J].
BOTTINI, G ;
CORCORAN, R ;
STERZI, R ;
PAULESU, E ;
SCHENONE, P ;
SCARPA, P ;
FRACKOWIAK, RSJ ;
FRITH, CD .
BRAIN, 1994, 117 :1241-1253
[5]  
Braver T. S., 1995, Society for Neuroscience Abstracts, V21, P274
[6]  
Cohen J D, 1994, Hum Brain Mapp, V1, P293, DOI 10.1002/hbm.460010407
[7]  
EDDY WF, P COMPUTATIONAL STAT
[8]   A METHOD FOR OBTAINING MEASURES OF LOCAL PARSING COMPLEXITY THROUGHOUT SENTENCES [J].
FORD, M .
JOURNAL OF VERBAL LEARNING AND VERBAL BEHAVIOR, 1983, 22 (02) :203-218
[9]   A GRADED TASK APPROACH TO THE FUNCTIONAL MAPPING OF BRAIN-AREAS IMPLICATED IN AUDITORY VERBAL MEMORY [J].
GRASBY, PM ;
FRITH, CD ;
FRISTON, KJ ;
SIMPSON, J ;
FLETCHER, PC ;
FRACKOWIAK, RSJ ;
DOLAN, RJ .
BRAIN, 1994, 117 :1271-1282
[10]  
HAARMANN HH, IN PRESS BRAIN LANG