Synthesis of a new carbocyclic nucleoside analog

被引：14

作者：

Bianco, A ^{[1
]}

Mazzei, RA ^{[1
]}

机构：

[1] CNR,CTR STUDIO CHIM SOSTANZE ORGAN NAT,I-00185 ROME,ITALY

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(97)01470-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of a new carbocyclic nucleoside, starting from a natural methylcyclopentanoid monoterpene, has been performed, allowing preparation of a carbovir analog, with a highly functionalized cyclopentane. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：6433 / 6436

页数：4

共 16 条

[11] The synthesis and biological evaluation of sulfamoyl nucleosides related to carbovir and AZT [J].

Vince, R ;

Pham, PT .

NUCLEOSIDES & NUCLEOTIDES, 1995, 14 (9-10) :2051-2060

[12] POTENT AND SELECTIVE ACTIVITY OF A NEW CARBOCYCLIC NUCLEOSIDE ANALOG (CARBOVIR-NSC-614846) AGAINST HUMAN IMMUNODEFICIENCY VIRUS INVITRO [J].

VINCE, R ;

HUA, M ;

BROWNELL, J ;

DALUGE, S ;

LEE, FC ;

SHANNON, WM ;

LAVELLE, GC ;

QUALLS, J ;

WEISLOW, OS ;

KISER, R ;

CANONICO, PG ;

SCHULTZ, RH ;

NARAYANAN, VL ;

MAYO, JG ;

SHOEMAKER, RH ;

BOYD, MR .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 156 (02) :1046-1053

[13] SYNTHESIS AND ANTI-HIV ACTIVITY OF CARBOCYCLIC 2',3'-DIDEHYDRO-2',3'-DIDEOXY 2,6-DISUBSTITUTED PURINE NUCLEOSIDES [J].

VINCE, R ;

HUA, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (01) :17-21

[14] NUCLEOSIDE SYNTHESES .25. A NEW SIMPLIFIED NUCLEOSIDE SYNTHESIS [J].

VORBRUGGEN, H ;

BENNUA, B .

CHEMISCHE BERICHTE-RECUEIL, 1981, 114 (04) :1279-1286

[15] NUCLEOSIDE SYNTHESES .23. ON THE MECHANISM OF NUCLEOSIDE SYNTHESIS [J].

VORBRUGGEN, H ;

HOFLE, G .

CHEMISCHE BERICHTE-RECUEIL, 1981, 114 (04) :1256-1268

[16] COMPARISON OF THE EFFECT OF CARBOVIR, AZT, AND DIDEOXYNUCLEOSIDE TRIPHOSPHATES ON THE ACTIVITY OF HUMAN IMMUNODEFICIENCY VIRUS REVERSE-TRANSCRIPTASE AND SELECTED HUMAN POLYMERASES [J].

WHITE, EL ;

PARKER, WB ;

MACY, LJ ;

SHADDIX, SC ;

MCCALEB, G ;

SECRIST, JA ;

VINCE, R ;

SHANNON, WM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 161 (02) :393-398

← 1 2 →