Synthesis of 2'-O,4'-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C-3,-endo sugar puckering

被引:501
作者
Obika, S
Nanbu, D
Hari, Y
Morio, K
In, Y
Ishida, T
Imanishi, T
机构
[1] OSAKA UNIV, FAC PHARMACEUT SCI, SUITA, OSAKA 565, JAPAN
[2] OSAKA UNIV PHARMACEUT SCI, TAKATSUKI, OSAKA 56911, JAPAN
关键词
D O I
10.1016/S0040-4039(97)10322-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
2'-O,4'-C-Methyleneuridine and -cytidine, novel bicyclic nucleoside analogs having a typical C3'-endo sugar puckering, were synthesized starting from uridine via a several-step sequence. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:8735 / 8738
页数:4
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