Synthesis of ODNs containing 4-methylamino-1,8-naphthalimide as a fluorescence probe in DNA

被引：34

作者：

Kawai, K ^{[1
]}

Kawabata, K ^{[1
]}

Tojo, S ^{[1
]}

Majima, T ^{[1
]}

机构：

[1] Osaka Univ, Inst Sci & Ind Res, SANKEN, Ibaraki, Osaka 5670047, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2002年 / 12卷 / 17期

关键词：

D O I：

10.1016/S0960-894X(02)00404-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthesis and fluorescence properties of oligodeoxynucleotides containing 4-methylamino-1,8-naphthalimide (NI) have been described. NI was successfully incorporated into DNA without significant destabilization of DNA whilst retaining its high fluorescence quantum yield. The attachment site of the NI greatly affected its property as an energy acceptor in FRET analysis. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2363 / 2366

页数：4

共 27 条

[1] Structural analysis of DNA bending induced by tethered triple helix forming oligonucleotides
Akiyama, T
Hogan, ME
[J]. BIOCHEMISTRY, 1997, 36 (08) : 2307 - 2315
[2] CLEGG RM, 1992, METHOD ENZYMOL, V211, P353
[3] Intramolecular photoinduced electron transfer to anthraquinones linked to duplex DNA: The effect of gaps and traps on long-range radical cation migration
Gasper, SM
Schuster, GB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (52) : 12762 - 12771
[4] Grabau A.W., 1931, PALAEONTOL SIN SER B, V3, P1
[5] Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer
Grunwell, JR
Glass, JL
Lacoste, TD
Deniz, AA
Chemla, DS
Schultz, PG
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (18) : 4295 - 4303
[6] Remote electronic control of DNA hybridization through inductive coupling to an attached metal nanocrystal antenna
Hamad-Schifferli, K
Schwartz, JJ
Santos, AT
Zhang, SG
Jacobson, JM
[J]. NATURE, 2002, 415 (6868) : 152 - 155
[7] SPECTROPHOTOMETRIC ASSAY FOR ENZYME-MEDIATED UNWINDING OF DOUBLE-STRANDED DNA
HOUSTON, P
KODADEK, T
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (12) : 5471 - 5474
[8] Sequential multistep energy transfer: enhancement of efficiency of long-range fluorescence resonance energy transfer
Kawahara, S
Uchimaru, T
Murata, S
[J]. CHEMICAL COMMUNICATIONS, 1999, (06) : 563 - 564
[9] DNA bending induced by high mobility group proteins studied by fluorescence resonance energy transfer
Lorenz, M
Hillisch, A
Payet, D
Buttinelli, M
Travers, A
Diekmann, S
[J]. BIOCHEMISTRY, 1999, 38 (37) : 12150 - 12158
[10] A nanomechanical device based on the B-Z transition of DNA
Mao, CD
Sun, WQ
Shen, ZY
Seeman, NC
[J]. NATURE, 1999, 397 (6715) : 144 - 146

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