Crow-fukase syndrome associated with high-output heart failure

被引：5

作者：

Araki, T ^{[1
]}

Konno, T ^{[1
]}

Soma, R ^{[1
]}

Nakashima, A ^{[1
]}

Takimoto, H ^{[1
]}

Tofuku, Y ^{[1
]}

Shimizu, M ^{[1
]}

机构：

[1] Saiseikai Kanazawa Hosp, Dept Internal Med, Kanazawa, Ishikawa, Japan

来源：

INTERNAL MEDICINE | 2002年 / 41卷 / 08期

关键词：

POEMS syndrome; vascular endothelial growth factor (VEGF); systemic vascular resistance;

D O I：

10.2169/internalmedicine.41.638

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 64-year-old woman was admitted with systemic edema and exertional dyspnea. High-output heart failure was diagnosed by right heart catheterization and she was treated with diuretics. After 3 weeks, her symptoms disappeared but a high cardiac output state persisted. A diagnosis of Crow-Fukase syndrome was made based on the presence of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes. Her serum vascular endothelial growth factor (VEGF) level was markedly elevated after recovery from heart failure. We suspect that an elevated VEGF level and a high cardiac output state may play a role in the pathogenesis of heart failure in Crow-Fukase syndrome.

引用

页码：638 / 641

页数：4

共 12 条

[1] PLASMA-CELL DYSCRASIA WITH POLYNEUROPATHY, ORGANOMEGALY, ENDOCRINOPATHY, M PROTEIN, AND SKIN CHANGES - THE POEMS SYNDROME - REPORT ON 2 CASES AND A REVIEW OF THE LITERATURE [J].

BARDWICK, PA ;

ZVAIFLER, NJ ;

GILL, GN ;

NEWMAN, D ;

GREENWAY, GD ;

RESNICK, DL .

MEDICINE, 1980, 59 (04) :311-322

[2]

BRAUMWALD E, 1997, HEART DIS TXB CARDIO, P460

[3]

Hood JD, 1998, AM J PHYSIOL-HEART C, V274, pH1054

[4] CROW-FUKASE SYNDROME-ASSOCIATED WITH PULMONARY-HYPERTENSION [J].

IWASAKI, H ;

OGAWA, K ;

YOSHIDA, H ;

TAKASHIMA, F ;

SHIMIZU, K ;

LEE, JD ;

UEDA, T ;

NAKAMURA, T .

INTERNAL MEDICINE, 1993, 32 (07) :556-560

[5] PREVALENCE AND CLINICAL CHARACTERISTICS OF A HIGH CARDIAC-OUTPUT STATE IN PATIENTS WITH MULTIPLE-MYELOMA [J].

MCBRIDE, W ;

JACKMAN, JD ;

GRAYBURN, PA .

AMERICAN JOURNAL OF MEDICINE, 1990, 89 (01) :21-24

[6] HIGH-OUTPUT CARDIAC-FAILURE IN PATIENTS WITH MULTIPLE-MYELOMA [J].

MCBRIDE, W ;

JACKMAN, JD ;

GAMMON, RS ;

WILLERSON, JT .

NEW ENGLAND JOURNAL OF MEDICINE, 1988, 319 (25) :1651-1653

[7] THE CROW-FUKASE SYNDROME - A STUDY OF 102 CASES IN JAPAN [J].

NAKANISHI, T ;

SOBUE, I ;

TOYOKURA, Y ;

NISHITANI, H ;

KUROIWA, Y ;

SATOYOSHI, E ;

TSUBAKI, T ;

IGATA, A ;

OZAKI, Y .

NEUROLOGY, 1984, 34 (06) :712-720

[8] VEGF is causative for pulmonary hypertension in a patient with Crow-Fukase (POEMS) syndrome [J].

Niimi, H ;

Arimura, K ;

Jonosono, M ;

Hashiguchi, T ;

Kawabata, M ;

Osame, M ;

Kitajima, I .

INTERNAL MEDICINE, 2000, 39 (12) :1101-1104

[9] THIAMINE-DEFICIENCY AND PULMONARY-HYPERTENSION IN CROW-FUKASE SYNDROME [J].

OKURA, H ;

GOHMA, I ;

HATTA, K ;

IMANAKA, T .

INTERNAL MEDICINE, 1995, 34 (07) :674-675

[10] Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration [J].

Podar, K ;

Tai, YT ;

Davies, FE ;

Lentzsch, S ;

Sattler, M ;

Hideshima, T ;

Lin, BK ;

Gupta, D ;

Shima, Y ;

Chauhan, D ;

Mitsiades, C ;

Raje, N ;

Richardson, P ;

Anderson, KC .

BLOOD, 2001, 98 (02) :428-435

← 1 2 →