A Rhodamine-Based Hg2+ Sensor with High Selectivity and Sensitivity in Aqueous Solution: A NS2-Containing Receptor

被引：291

作者：

Huang, Junhai ^{[1
]}

Xu, Yufang ^{[1
]}

Qian, Xuhong ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Sch Pharm, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 05期

基金：

国家高技术研究发展计划(863计划); 中国国家自然科学基金;

关键词：

ON FLUORESCENT SENSOR; TURN-ON; HG2+-SELECTIVE CHEMODOSIMETER; CHEMOSENSOR; PROBE; SPIROLACTAM; IONS; RECOGNITION; BIOLOGY; DESIGN;

D O I：

10.1021/jo802297x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rhodamine-based sensor 1 was designed and synthesized by in corporation the rhodamine fluorophore and ionophore NS2 with high affinity to Hg2+. Sensor 1 exhibits a high selectivity and an excellent sensitivity and is a dual-responsive colorimetric and fluorescent Hg2+-specific sensor in aqueous buffer solution. In addition, the 1:1 binding mode was proposed based on the H-1 NMR and ES(+)MS studies.

引用

页码：2167 / 2170

页数：4

共 46 条

[1] Dual-mode semisquaraine-based sensor for selective detection of Hg2+ in a micellar medium [J].

Avirah, Rekha R. ;

Jyothish, Kuthanapillil ;

Ramaiah, Danaboyina .

ORGANIC LETTERS, 2007, 9 (01) :121-124

[2] Rhodamine-hydroxamate-based fluorescent chemosensor for FeIII [J].

Bae, Shinhyo ;

Tae, Jinsung .

TETRAHEDRON LETTERS, 2007, 48 (31) :5389-5392

[3] A highly selective and sensitive fluorescence probe for the hypochlorite anion [J].

Chen, Xinqi ;

Wang, Xiaochun ;

Wang, Shajuan ;

Shi, Wen ;

Wang, Ke ;

Ma, Huimin .

CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (15) :4719-4724

[4] Signal ratio amplification via modulation of resonance energy transfer: Proof of principle in an emission ratiometric Hg(II) sensor [J].

Coskun, Ali ;

Akkaya, Engin U. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (45) :14474-14475

[5] Signaling recognition events with fluorescent sensors and switches [J].

de Silva, AP ;

Gunaratne, HQN ;

Gunnlaugsson, T ;

Huxley, AJM ;

McCoy, CP ;

Rademacher, JT ;

Rice, TE .

CHEMICAL REVIEWS, 1997, 97 (05) :1515-1566

[6] Coupling selectivity with sensitivity in an integrated chemosensor framework:: Design of a Hg2+-responsive probe, operating above 500 nm [J].

Descalzo, AB ;

Martínez-Máñez, R ;

Radeglia, R ;

Rurack, K ;

Soto, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (12) :3418-3419

[7] Synthetic fluorescent sensors for studying the cell biology of metals [J].

Domaille, Dylan W. ;

Que, Emily L. ;

Chang, Christopher J. .

NATURE CHEMICAL BIOLOGY, 2008, 4 (03) :168-175

[8] A long-wavelength fluorescent chemodosimeter selective for Cu(II) ion in water [J].

Dujols, V ;

Ford, F ;

Czarnik, AW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (31) :7386-7387

[9] A highly selective and sensitive fluorescent chemosensor for Hg2+ in neutral buffer aqueous solution [J].

Guo, XF ;

Qian, XH ;

Jia, LH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (08) :2272-2273

[10]

Haugland R.P., 2005, HDB GUIDE FLUORESCEN, V10th

← 1 2 3 4 5 →