Second-harmonic optical coherence tomography

被引：74

作者：

Jiang, Y ^{[1
]}

Tomov, I

Wang, YM

Chen, ZP

机构：

[1] Univ Calif Irvine, Becknam Laser Inst, Irvine, CA 92612 USA

[2] Univ Calif Irvine, Dept Biomed Engn, Irvine, CA 92612 USA

来源：

OPTICS LETTERS | 2004年 / 29卷 / 10期

关键词：

D O I：

10.1364/OL.29.001090

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Second-harmonic optical coherence tomography, which uses coherence gating of second-order nonlinear optical responses of biological tissues for imaging, is described and demonstrated. Femtosecond laser pulses were used to excite second-harmonic waves from collagen harvested from rat tail tendon and a reference nonlinear crystal. Second-harmonic interference fringe signals were detected and used for image construction. Because of the strong dependence of second-harmonic generation on molecular and tissue structures, this technique imparts contrast and resolution enhancement to conventional optical coherence tomography. (C) 2004 Optical Society of America

引用

页码：1090 / 1092

页数：3

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