Aryl trihydroxyborates: Easily isolated discrete species convenient for direct application in coupling reactions

被引：99

作者：

Cammidge, Andrew N. ^{[1
]}

Goddard, Victoria H. M.

Gopee, Hemant

Harrison, Nicola L.

Hughes, David L.

Schubert, Christopher J.

Sutton, Benjamin M.

Watts, Gary L.

Whitehead, Andrew J.

机构：

[1] Univ E Anglia, Sch Chem Sci & Pharm, Norwich, Norfolk, England

[2] GSK Pharmaceut, Stevenage SG1 2NY, Herts, England

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 18期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1021/ol061564w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A conceptually and practically simple alternative approach to the use of arylboron species as the organometallic component in cross-coupling processes is described whereby trihydroxyborate salts are isolated and directly employed. The protocol derives practical benefit from the ease and convenience of the isolation and subsequent use of the discrete borate salts, eliminates the need for additional base, and aids the use of correct reaction stoichiometry.

引用

页码：4071 / 4074

页数：4

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