Reaction of nitroorganic compounds using thiourea catalysts anchored to polymer support

被引：48

作者：

Miyabe, Hideto

Tuchida, Sayo

Yamauchi, Masashige

Takemoto, Yoshiji ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Pharmaceut Sci, Sakyo Ku, Kyoto 6068501, Japan

[2] Josai Univ, Fac Pharmaceut Sci, Sakado, Saitama 3500295, Japan

来源：

SYNTHESIS-STUTTGART | 2006年 / 19期

关键词：

organocatalyst; thiourea; enantioselective; polymer support; PEG;

D O I：

10.1055/s-2006-950196

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Immobilization of chiral thiourea catalyst was studied. The PEG-bound thiourea showed better catalytic activity than those of the carboxypolystyrene HL resin-bound and TentaGel carboxy resin-bound thioureas. In the presence of PEG-bound thiourea, Michael and tandem Michael reactions of trans-beta-nitrostyrene proceeded enantioselectively.

引用

页码：3295 / 3300

页数：6

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