Chance and design - Proton transfer in water, channels and bioenergetic proteins

被引:324
作者
Wraight, Colin A. [1 ]
机构
[1] Univ Illinois, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA
来源
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | 2006年 / 1757卷 / 08期
关键词
D O I
10.1016/j.bbabio.2006.06.017
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Proton transfer and transport in water, gramicidin and some selected channels and bioenergetic proteins are reviewed. An attempt is made to draw some conclusions about how Nature designs long distance, proton transport functionality. The prevalence of water rather than amino acid hydrogen bonded chains is noted, and the possible benefits of waters as the major component are discussed qualitatively. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:886 / 912
页数:27
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