Retrotransposon-gene associations are widespread among D-melanogaster populations

被引：32

作者：

Franchini, LF ^{[1
]}

Ganko, EW ^{[1
]}

McDonald, JF ^{[1
]}

机构：

[1] Univ Georgia, Dept Genet, Athens, GA 30602 USA

来源：

MOLECULAR BIOLOGY AND EVOLUTION | 2004年 / 21卷 / 07期

关键词：

long terminal repeats; retrotransposons; transposable elements; Drosophila melanogaster; genome evolution;

D O I：

10.1093/molbev/msh116

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have surveyed 18 natural populations of Drosophila melanogaster for the presence of 23 retrotransposon-gene-association alleles (i.e., the presence of an LTR retrotransposon sequence in or within 1,000 bp of a gene) recently identified in the sequenced D. melanogaster genome. The identified associations were detected only in the D. melanogaster populations. The majority (61%) of the identified retrotransposon-gene associations were present only in the sequenced strain in which they were first identified. Thirty percent of the associations were detected in at least one of the natural populations, and 9% of the associations were detected in all of the D. melanogaster populations surveyed. Sequence analysis of an association allele present in all populations indicates that selection is a significant factor in the spread and/or maintenance of at least some of retroelement-gene associations in D. melanogaster.

引用

页码：1323 / 1331

页数：9

共 42 条

[21] Origin of a substantial fraction of human regulatory sequences from transposable elements [J].

Jordan, IK ;

Rogozin, IB ;

Glazko, GV ;

Koonin, EV .

TRENDS IN GENETICS, 2003, 19 (02) :68-72

[22]

Jordan IK, 1999, GENETICS, V151, P1341

[23]

KAMINKER JS, 2002, GENOME BIOL, V0003

[24] Transposable elements and the evolution of genome size in eukaryotes [J].

Kidwell, MG .

GENETICA, 2002, 115 (01) :49-63

[25] Initial sequencing and analysis of the human genome [J].

Lander, ES ;

Int Human Genome Sequencing Consortium ;

Linton, LM ;

Birren, B ;

Nusbaum, C ;

Zody, MC ;

Baldwin, J ;

Devon, K ;

Dewar, K ;

Doyle, M ;

FitzHugh, W ;

Funke, R ;

Gage, D ;

Harris, K ;

Heaford, A ;

Howland, J ;

Kann, L ;

Lehoczky, J ;

LeVine, R ;

McEwan, P ;

McKernan, K ;

Meldrim, J ;

Mesirov, JP ;

Miranda, C ;

Morris, W ;

Naylor, J ;

Raymond, C ;

Rosetti, M ;

Santos, R ;

Sheridan, A ;

Sougnez, C ;

Stange-Thomann, N ;

Stojanovic, N ;

Subramanian, A ;

Wyman, D ;

Rogers, J ;

Sulston, J ;

Ainscough, R ;

Beck, S ;

Bentley, D ;

Burton, J ;

Clee, C ;

Carter, N ;

Coulson, A ;

Deadman, R ;

Deloukas, P ;

Dunham, A ;

Dunham, I ;

Durbin, R ;

French, L .

NATURE, 2001, 409 (6822) :860-921

[26] Repetitive elements in the 5′ untranslated region of a human zinc-finger gene modulate transcription and translation efficiency [J].

Landry, JR ;

Medstrand, P ;

Mager, DL .

GENOMICS, 2001, 76 (1-3) :110-116

[27] Modification of heat-shock gene expression in Drosophila melanogaster populations via transposable elements [J].

Lerman, DN ;

Michalak, P ;

Helin, AB ;

Bettencourt, BR ;

Feder, ME .

MOLECULAR BIOLOGY AND EVOLUTION, 2003, 20 (01) :135-144

[28] Inferences on the evolutionary history of the S-element family of Drosophila melanogaster [J].

Maside, X ;

Bartolomé, C ;

Charlesworth, B .

MOLECULAR BIOLOGY AND EVOLUTION, 2003, 20 (08) :1183-1187

[29] CHROMOSOME ORGANIZATION AND GENIC EXPRESSION [J].

MCCLINTOCK, B .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1951, 16 :13-47

[30] MACROEVOLUTION AND RETROVIRAL ELEMENTS [J].

MCDONALD, JF .

BIOSCIENCE, 1990, 40 (03) :183-191

← 1 2 3 4 5 →