N-H insertion reactions of rhodium carbenoids .1. Preparation of alpha-amino acid and alpha-aminophosphonic acid derivatives

被引：77

作者：

Aller, E

Buck, RT

Drysdale, MJ

Ferris, L

Haigh, D

Moody, CJ

Pearson, ND

Sanghera, JB

机构：

[1] LOUGHBOROUGH UNIV TECHNOL,DEPT CHEM,LOUGHBOROUGH LE11 3TU,LEICS,ENGLAND

[2] GLAXO WELLCOME RES & DEV LTD,MED RES CTR,STEVENAGE SG1 2NY,HERTS,ENGLAND

[3] SMITHKLINE BEECHAM PHARMACEUT,EPSOM KT18 5XQ,SURREY,ENGLAND

[4] SMITHKLINE BEECHAM PHARMACEUT,BETCHWORTH RH3 7AL,SURREY,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 24期

关键词：

D O I：

10.1039/p19960002879

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rhodium(II) acetate-catalysed decomposition of diazophenylacetates 1 and 3 in the presence of a range of N-H compounds results in an N-H insertion reaction of the intermediate carbenoids and formation of N-substituted phenylglycine derivatives 2 and 4. The corresponding reactions of dimethyl alpha-diazobenzylphosphonate 5 constitute a simple route to aminophosphonates 6.

引用

页码：2879 / 2884

页数：6

共 82 条

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