Antisense RNA in imprinting:: spreading silence through Air

被引：62

作者：

Rougeulle, C

Heard, E

机构：

[1] Inst Pasteur, Unite Genet Mol Murine, F-75015 Paris, France

[2] Inst Curie, CNRS, UMR 218, F-75005 Paris, France

来源：

TRENDS IN GENETICS | 2002年 / 18卷 / 09期

关键词：

D O I：

10.1016/S0168-9525(02)02749-X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In some animals, including mammals, a number of genes are expressed differently according to whether they have been inherited from the mother or from the father, through a process known as genomic imprinting. Noncoding RNAs have increasingly been found associated with imprinted genes, but their role, if any, has remained enigmatic. A recent study provides the first evidence that, at least in one case, a noncoding RNA has a direct role in regulating imprinted gene expression in cis.

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收藏

页码：434 / 437

页数：4

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