Axis development: The mouse becomes a dachshund

被引：13

作者：

Gad, JM ^{[1
]}

Tan, PPL ^{[1
]}

机构：

[1] Univ Sydney, Childrens Med Res Inst, Embryol Unit, Sydney, NSW 2006, Australia

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 20期

关键词：

D O I：

10.1016/S0960-9822(00)80013-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Targeted deletion of the gene for GDF11, a novel member of the TGF beta family, has been found to cause an increase in the number of thoracic and lumbar vertebrae in the mouse. This is the first hint that a secreted factor may influence the specification of segment identity.

引用

页码：R783 / R786

页数：4

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