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Comparative in vitro efficacies of various catheter lock solutions

被引：96
作者：
Sherertz, RJ
Boger, MS
Collins, CA
Mason, L
Raad, II
机构：
[1] Wake Forest Univ, Sch Med, Infect Dis Sect, Dept Internal Med, Winston Salem, NC 27517 USA
[2] N Carolina Baptist Hosp, Dept Infect Control, Winston Salem, NC 27103 USA
[3] Univ Texas, MD Anderson Canc Ctr, Dept Infect Dis Infect Control & Employee Hlth, Houston, TX 77030 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 05期
关键词：
D O I：
10.1128/AAC.50.5.1865-1868.2006
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
MEDTA (minocycline-edetate calcium disodium), taurolidine (2%)-polyvinylpyrolidine (50%) (T/PVP), and ethanol as potential catheter lock solutions have a unique mechanism of action, broad-spectrum activity, and anticoagulant properties. Traditional lock solutions minocycline (M), rifampin (R), ciprofloxacin (C), and vancomycin, except pharmacologic concentrations of C and R and of M and R, were less effective than MEDTA and T/PVP.
引用
收藏
页码：1865 / 1868
页数：4
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