Comparative in vitro efficacies of various catheter lock solutions

被引：96

作者：

Sherertz, RJ

Boger, MS

Collins, CA

Mason, L

Raad, II

机构：

[1] Wake Forest Univ, Sch Med, Infect Dis Sect, Dept Internal Med, Winston Salem, NC 27517 USA

[2] N Carolina Baptist Hosp, Dept Infect Control, Winston Salem, NC 27103 USA

[3] Univ Texas, MD Anderson Canc Ctr, Dept Infect Dis Infect Control & Employee Hlth, Houston, TX 77030 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 05期

关键词：

D O I：

10.1128/AAC.50.5.1865-1868.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

MEDTA (minocycline-edetate calcium disodium), taurolidine (2%)-polyvinylpyrolidine (50%) (T/PVP), and ethanol as potential catheter lock solutions have a unique mechanism of action, broad-spectrum activity, and anticoagulant properties. Traditional lock solutions minocycline (M), rifampin (R), ciprofloxacin (C), and vancomycin, except pharmacologic concentrations of C and R and of M and R, were less effective than MEDTA and T/PVP.

引用

页码：1865 / 1868

页数：4

共 48 条

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