Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules

被引：38

作者：

Calixto, JB

Campos, MM

Otuki, MF

Santos, ARS

机构：

[1] Univ Fed Santa Catarina, Dept Pharmacol, CCB, BR-88015420 Florianopolis, SC, Brazil

[2] Univ Fed Santa Catarina, Dept Physiol Sci, CCB, BR-88015420 Florianopolis, SC, Brazil

来源：

PLANTA MEDICA | 2004年 / 70卷 / 02期

关键词：

medicinal plants; plant constituents; inflammation; cytokines; chemokines; adhesion molecules;

D O I：

10.1055/s-2004-815483

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

It has been widely shown that many plant-derived compounds present significant anti-inflammatory effects. For this reason, they represent potential molecules for the development of new drugs, especially designed for the treatment and/or control of chronic inflammatory states such as rheumatism, asthma, inflammatory bowel diseases, atherosclerosis, etc. This review focuses on the naturally-occurring compounds with anti-inflammatory properties and attempts to correlate their actions with the modulation of cytokines and associated intracellular signalling pathways; it continues the review published in the November, 2003 issue of Planta Medica.

引用

收藏

页码：93 / 103

页数：11

相关论文

共 106 条

[41]

GERRITSEN ME, 1995, AM J PATHOL, V147, P278

[42] Natural inhibitors of tumour necrosis factor-α production, secretion and function [J].

Habtemariam, S .

PLANTA MEDICA, 2000, 66 (04) :303-313

[43] Cytokines and related receptor-mediated signaling pathways [J].

Haddad, JJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 297 (04) :700-713

[44] Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes [J].

Hart, PH ;

Brand, C ;

Carson, CF ;

Riley, TV ;

Prager, RH ;

Finlay-Jones, JJ .

INFLAMMATION RESEARCH, 2000, 49 (11) :619-626

[45] Hematein inhibits tumor necrotic factor-α-induced vascular cell adhesion molecule-1 and NF-κB-dependent gene expression in human vascular endothelial cells [J].

Hong, JJ ;

Jeong, TS ;

Choi, JH ;

Park, JH ;

Lee, KY ;

Seo, YJ ;

Oh, SR ;

Oh, GT .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 281 (05) :1127-1133

[46]

Hopkins Stephen John, 2003, Leg Med (Tokyo), V5 Suppl 1, pS45, DOI 10.1016/S1344-6223(02)00088-3

[47] Novel cytokine release inhibitors. Part I: Triterpenes [J].

Huang, FC ;

Chan, WK ;

Moriarty, KJ ;

Zhang, DC ;

Chang, MN ;

He, W ;

Yu, KT ;

Zilberstein, A .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (14) :1883-1886

[48] Effect of sesquiterpene lactones on the expression of the activation marker CD69 and of IL-2 in T-lymphocytes in whole blood [J].

Humar, M ;

García-Piñeres, AJ ;

Castro, V ;

Merfort, I .

BIOCHEMICAL PHARMACOLOGY, 2003, 65 (09) :1551-1563

[49] Four new clerodane diterpenes from the leaves of Casearia guianensis which inhibit the interaction of leukocyte function antigen 1 with intercellular adhesion molecule 1 [J].

Hunter, MS ;

Corley, DG ;

Carron, CP ;

Rowold, E ;

Kilpatrick, BF ;

Durley, RC .

JOURNAL OF NATURAL PRODUCTS, 1997, 60 (09) :894-899

[50] Inhibition of lipopolysaccharide-induced pro-inflammatory cytokine expression via suppression of nuclear factor-κB activation by Mallotus japonicus phloroglucinol derivatives [J].

Ishii, R ;

Horie, M ;

Saito, K ;

Arisawa, M ;

Kitanaka, S .

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2003, 1620 (1-3) :108-118

← 1 2 3 4 5 6 7 8 9 10 →