Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice

被引：88

作者：

Burger, O

Weiss, E

Sharon, N

Tabak, M

Neeman, I

Ofek, I ^{[1
]}

机构：

[1] Tel Aviv Univ, Sackler Fac Med, Dept Human Microbiol, IL-69978 Tel Aviv, Israel

[2] Tel Aviv Univ, Maurice & Gabriela Goldschleger Sch Dent Med, IL-69978 Tel Aviv, Israel

[3] Technion Israel Inst Technol, Inst Technol, Fac Food Engn & Biotechnol, Haifa, Israel

[4] Weizmann Inst Sci, IL-76100 Rehovot, Israel

来源：

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION | 2002年 / 42卷 / 03期

关键词：

Helicobacter pylori; cranberry; mucus; adhesion;

D O I：

10.1080/10408390209351916

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

A high-molecular-weight constituent of cranberry juice has been found to inhibit the sialyllactose specific adhesion of Helicobacter pylori strains to immobilized human mucus, erythrocytes, and cultured gastric epithelial cells. Different isolates of H. pylori differ in their affinity to the cranberry juice constituent. Cranberry juice may also inhibit adhesion of bacteria to the stomach in vivo, and may prove useful for the prevention of stomach ulcer that is caused by H. pylori.

引用

页码：279 / 284

页数：6

共 21 条

[1] Isolation of a cell surface component of Helicobacter pylori that binds H type 2, Lewis(a), and Lewis(b) antigens [J].