Measurement of the arterial concentration of Gd-DTPA using MRI: A step toward quantitative perfusion imaging

被引：198

作者：

FritzHansen, T ^{[1
]}

Rostrup, E ^{[1
]}

Larsson, HBW ^{[1
]}

Sondergaard, L ^{[1
]}

Ring, P ^{[1
]}

Henriksen, O ^{[1
]}

机构：

[1] UNIV COPENHAGEN,HVIDOVRE HOSP,DEPT CLIN PHYSIOL & NUCL MED,DK-2650 HVIDOVRE,DENMARK

来源：

MAGNETIC RESONANCE IN MEDICINE | 1996年 / 36卷 / 02期

关键词：

arterial input function; gadolinium-DTPA; MRI; turbo-FLASH;

D O I：

10.1002/mrm.1910360209

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A noninvasive method using an inversion recovery turbo-FLASH for dynamic measurement of the arterial input function represented by the bolus passage of Gd-DTPA in the descending aorta is presented, and the results are compared with the input function obtained by arterial blood samples. A good accordance between the two input functions was found, indicating that it is possible to measure the input function to the myocardium using MRI. A variation between the two concentration curves of 5% at upslope, 2.7% at peak point, and <7% at downslope was found. The study also indicates that a short inversion time <250 ms has to be used to ensure correct measurement of peak concentration.

引用

页码：225 / 231

页数：7

共 19 条

[1] SPIN-LATTICE RELAXATION-TIME MEASUREMENT BY MEANS OF A TURBOFLASH TECHNIQUE [J].

BLUML, S ;

SCHAD, LR ;

STEPANOW, B ;

LORENZ, WJ .

MAGNETIC RESONANCE IN MEDICINE, 1993, 30 (03) :289-295

[2] FACTORS IN MYOCARDIAL PERFUSION IMAGING WITH ULTRAFAST MRI AND GD-DTPA ADMINISTRATION [J].

BURSTEIN, D ;

TARATUTA, E ;

MANNING, WJ .

MAGNETIC RESONANCE IN MEDICINE, 1991, 20 (02) :299-305

[3] ADVANCES IN CARDIAC APPLICATIONS OF SUBSECOND FLASH MRI [J].

CHIEN, D ;

MERBOLDT, KD ;

HANICKE, W ;

BRUHN, H ;

GYNGELL, ML ;

FRAHM, J .

MAGNETIC RESONANCE IMAGING, 1990, 8 (06) :829-836

[4] NICKEL-DOPED AGAROSE-GEL PHANTOMS IN MR IMAGING [J].

CHRISTOFFERSSON, JO ;

OLSSON, LE ;

SJOBERG, S .

ACTA RADIOLOGICA, 1991, 32 (05) :426-431

[5] QUANTIFICATION OF MYOCARDIAL BLOOD-FLOW AND EXTRACELLULAR VOLUMES USING A BOLUS INJECTION OF GD-DTPA - KINETIC MODELING IN CANINE ISCHEMIC DISEASE [J].

DIESBOURG, LD ;

PRATO, FS ;

WISENBERG, G ;

DROST, DJ ;

MARSHALL, TP ;

CARROLL, SE ;

ONEILL, B .

MAGNETIC RESONANCE IN MEDICINE, 1992, 23 (02) :239-253

[6]

FRITZHANSEN T, 1995, P SMR 3 ANN M, P878

[7] MEASUREMENT OF ABSOLUTE BLOOD IODINE CONCENTRATION DURING DIGITAL SUBTRACTION VENTRICULOGRAPHY [J].

FUERST, TP ;

VANLYSEL, MS .

MEDICAL PHYSICS, 1993, 20 (03) :795-803

[8] NUCLEAR MAGNETIC-RESONANCE SIGNAL FROM FLOWING NUCLEI IN RAPID IMAGING USING GRADIENT ECHOES [J].

GAO, JH ;

HOLLAND, SK ;

GORE, JC .

MEDICAL PHYSICS, 1988, 15 (06) :809-814

[9] ERROR ANALYSIS OF A QUANTITATIVE CEREBRAL BLOOD-FLOW MEASUREMENT USING (H2O)-O-15 AUTORADIOGRAPHY AND POSITRON EMISSION TOMOGRAPHY, WITH RESPECT TO THE DISPERSION OF THE INPUT FUNCTION [J].

IIDA, H ;

KANNO, I ;

MIURA, S ;

MURAKAMI, M ;

TAKAHASHI, K ;

UEMURA, K .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1986, 6 (05) :536-545

[10] A SYSTEM FOR CEREBRAL BLOOD-FLOW MEASUREMENT USING AN (H2O)-O-15 AUTORADIOGRAPHIC METHOD AND POSITRON EMISSION TOMOGRAPHY [J].

KANNO, I ;

IIDA, H ;

MIURA, S ;

MURAKAMI, M ;

TAKAHASHI, K ;

SASAKI, H ;

INUGAMI, A ;

SHISHIDO, F ;

UEMURA, K .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1987, 7 (02) :143-153

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