Benzylic Carbon Oxidation by an in situ Formed o-Iodoxybenzoic Acid (IBX) Derivative

被引：46

作者：

Ojha, Lawanya R. ^{[1
]}

Kudugunti, Shashi ^{[1
]}

Maddukuri, Padma P. ^{[1
]}

Kommareddy, Amitha ^{[1
]}

Gunna, Meena R. ^{[1
]}

Dokuparthi, Praveen ^{[1
]}

Gottam, Hima B. ^{[1
]}

Botha, Kiran K. ^{[1
]}

Parapati, Divya R. ^{[1
]}

Vinod, Thottumkara K. ^{[1
]}

机构：

[1] Western Illinois Univ, Dept Chem, Macomb, IL 61455 USA

来源：

SYNLETT | 2009年 / 01期

基金：

美国国家科学基金会;

关键词：

oxidation; o-iodoxybenzoic acid (IBX); single-electron transfer; rearrangement; Oxone (R); C-H BONDS; TERT-BUTYL; TEMPERATURE; GENERATION; CONVERSION; ALDEHYDES; ALCOHOLS; OXYGEN; MILD;

D O I：

10.1055/s-0028-1087384

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzylic C-H bonds are selectively oxidized to the corresponding carbonyl functionalities using catalytic quantities of 2-iodobenzoic acid (2IBAcid) and Oxone (R). The reported procedure tolerates different functional groups and operates under mild conditions. A radical mechanism is proposed for the transfomation and evidence supporting the proposed mechanism is also presented.

引用

页码：117 / 121

页数：5

共 38 条

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