A Monte Carlo dose calculation tool for radiotherapy treatment planning

被引:142
作者
Ma, CM [1 ]
Li, JS
Pawlicki, T
Jiang, SB
Deng, J
Lee, MC
Koumrian, T
Luxton, M
Brain, S
机构
[1] Stanford Univ, Sch Med, Dept Radiat Oncol, Stanford, CA 94305 USA
[2] Fox Chase Canc Ctr, Dept Radiat Oncol, Philadelphia, PA 19111 USA
关键词
D O I
10.1088/0031-9155/47/10/305
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A Monte Carlo user code, MCDOSE, has been developed for radiotherapy treatment planning (RTP) dose calculations. MCDOSE is designed as a dose calculation module suitable for adaptation to host RTP systems. MCDOSE can be used for both conventional photon/electron beam calculation and intensity modulated radiotherapy (IMRT) treatment planning. MCDOSE uses a multiple-source model to reconstruct the treatment beam phase space. Based on Monte Carlo simulated or measured beam data acquired during commissioning, source-model parameters are adjusted through an automated procedure. Beam modifiers such as jaws. physical and dynamic wedges. compensators. blocks, electron cut-outs and bolus are simulated by MCDOSE together with a 3D rectilinear patient geometry model built from CT data. Dose distributions calculated using MCDOSE agreed well with those calculated by the EGS4/DOSXYZ code using different beam set-ups and beam modifiers. Heterogeneity correction factors for layered-lung or layered-bone phantoms as calculated by both codes were consistent with measured data to within 1%. The effect of energy cut-offs for particle transport was investigated. Variance reduction techniques were implemented in MCDOSE to achieve a speedup factor of 10-30 compared to DOSXYZ.
引用
收藏
页码:1671 / 1689
页数:19
相关论文
共 52 条
[1]   MONTE-CARLO TECHNIQUES IN MEDICAL RADIATION PHYSICS [J].
ANDREO, P .
PHYSICS IN MEDICINE AND BIOLOGY, 1991, 36 (07) :861-920
[2]  
[Anonymous], 1994, P 11 ICCR MANCH UK
[3]   The impact of electron transport on the accuracy of computed dose [J].
Arnfield, MR ;
Siantar, CH ;
Siebers, J ;
Garmon, P ;
Cox, L ;
Mohan, R .
MEDICAL PHYSICS, 2000, 27 (06) :1266-1274
[4]  
Bielajew A., 1990, The Dosimetry of Ionizing Radiation, Volume, P427
[5]  
BIELAJEW AF, 1987, NUCL INSTRUM METH B, V18, P165
[6]  
BIELAJEW AF, 1987, USE COMPUTERS RAD TH, P65
[7]   Calculation of x-ray transmission through a multileaf collimator [J].
Chen, Y ;
Boyer, AL ;
Ma, CM .
MEDICAL PHYSICS, 2000, 27 (08) :1717-1726
[8]   ELECTRON DOSE DISTRIBUTIONS IN EXPERIMENTAL PHANTOMS - A COMPARISON WITH 2D PENCIL BEAM CALCULATIONS [J].
CYGLER, J ;
BATTISTA, JJ ;
SCRIMGER, JW ;
MAH, E ;
ANTOLAK, J .
PHYSICS IN MEDICINE AND BIOLOGY, 1987, 32 (09) :1073-1086
[9]   CT-based Monte Carlo simulation tool for dosimetry planning and analysis [J].
DeMarco, JJ ;
Solberg, TD ;
Smathers, JB .
MEDICAL PHYSICS, 1998, 25 (01) :1-11
[10]   The MLC tongue-and-groove effect on IMRT dose distributions [J].
Deng, J ;
Pawlicki, T ;
Chen, Y ;
Li, JS ;
Jiang, SB ;
Ma, CM .
PHYSICS IN MEDICINE AND BIOLOGY, 2001, 46 (04) :1039-1060