A Monte Carlo dose calculation tool for radiotherapy treatment planning

被引:142
作者
Ma, CM [1 ]
Li, JS
Pawlicki, T
Jiang, SB
Deng, J
Lee, MC
Koumrian, T
Luxton, M
Brain, S
机构
[1] Stanford Univ, Sch Med, Dept Radiat Oncol, Stanford, CA 94305 USA
[2] Fox Chase Canc Ctr, Dept Radiat Oncol, Philadelphia, PA 19111 USA
关键词
D O I
10.1088/0031-9155/47/10/305
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A Monte Carlo user code, MCDOSE, has been developed for radiotherapy treatment planning (RTP) dose calculations. MCDOSE is designed as a dose calculation module suitable for adaptation to host RTP systems. MCDOSE can be used for both conventional photon/electron beam calculation and intensity modulated radiotherapy (IMRT) treatment planning. MCDOSE uses a multiple-source model to reconstruct the treatment beam phase space. Based on Monte Carlo simulated or measured beam data acquired during commissioning, source-model parameters are adjusted through an automated procedure. Beam modifiers such as jaws. physical and dynamic wedges. compensators. blocks, electron cut-outs and bolus are simulated by MCDOSE together with a 3D rectilinear patient geometry model built from CT data. Dose distributions calculated using MCDOSE agreed well with those calculated by the EGS4/DOSXYZ code using different beam set-ups and beam modifiers. Heterogeneity correction factors for layered-lung or layered-bone phantoms as calculated by both codes were consistent with measured data to within 1%. The effect of energy cut-offs for particle transport was investigated. Variance reduction techniques were implemented in MCDOSE to achieve a speedup factor of 10-30 compared to DOSXYZ.
引用
收藏
页码:1671 / 1689
页数:19
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