Chromosome cohesion: ring around the sisters?

被引:24
作者
Campbell, JL [1 ]
Cohen-Fix, O [1 ]
机构
[1] NIDDK, Lab Mol & Cellular Biol, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1016/S0968-0004(02)02194-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Sister chromatid cohesion is a key aspect of accurate chromosome transmission during mitosis, yet little is known about the structure of cohesin, the protein complex that links the two sister chromatids. Recent studies shed light on the structure of the cohesin complex, leading to intriguing models that could explain how sister chromatids are held together.
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页码:492 / 495
页数:4
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