Effect of Upper Limb Botulinum Toxin Injections on Impairment, Activity, Participation, and Quality of Life Among Stroke Patients

被引：35

作者：

Caty, Gilles D. ^{[1
]}

Detrembleur, Christine ^{[1
]}

Bleyenheuft, Corinne ^{[1
]}

Deltombe, Thierry ^{[2
]}

Lejeune, Thierry M. ^{[1
]}

机构：

[1] Catholic Univ Louvain, Clin Univ St Luc, Dept Phys Med & Rehabil, B-1200 Brussels, Belgium

[2] Catholic Univ Louvain, Clin Univ Mt Godinne, Dept Phys Med & Rehabil, Yvoir, Belgium

来源：

STROKE | 2009年 / 40卷 / 07期

关键词：

stroke; arm; spasticity; Botulinum toxins; POSTSTROKE SPASTICITY;

D O I：

10.1161/STROKEAHA.108.544346

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Background and Purpose-The purpose of this study was to study the effect of Botulinum toxin type A (BoNT-A) injections in spastic upper limb muscles on impairment, activity, participation and quality of life in chronic stroke patients. Methods-BoNT-A (Dysport) was injected into several upper limb spastic muscles in a group of 20 patients. Neurological impairment (muscle tone and strength, dexterity, SIAS), activity (ABILHAND), participation (SATIS-Stroke), and quality of life (SF36) were assessed before and 2 months after the injections. Results-BoNT-A injections improved muscle tone, but had no impact on dexterity, manual ability, social participation, and quality of life. Conclusions-In this study, BoNT-A injections in spastic upper limbs significantly reduced neurological impairments, but had no functional impact. (Stroke. 2009; 40: 2589-2591.)

引用

页码：2589 / 2591

页数：3

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