Tumor Exome Analysis Reveals Neoantigen-Specific T-Cell Reactivity in an Ipilimumab-Responsive Melanoma

被引:688
作者
van Rooij, Nienke [1 ]
van Buuren, Marit M. [1 ]
Philips, Daisy [1 ]
Velds, Arno [1 ]
Toebes, Mireille [1 ]
Heemskerk, Bianca [1 ]
van Dijk, Laura J. A. [1 ]
Behjati, Sam [2 ]
Hilkmann, Henk [1 ]
el Atmioui, Dris [1 ]
Nieuwland, Marja [1 ]
Stratton, Michael R. [2 ]
Kerkhoven, Ron M. [1 ]
Kesmir, Can [3 ]
Haanen, John B. [1 ]
Kvistborg, Pia [1 ]
Schumacher, Ton N. [1 ]
机构
[1] Netherlands Canc Inst, Amsterdam, Netherlands
[2] Wellcome Trust Sanger Inst, Cambridge, England
[3] Univ Utrecht, Utrecht, Netherlands
基金
英国惠康基金;
关键词
MHC CLASS-I; PARALLEL DETECTION; CANCER; ANTIBODY; PREDICTIONS; MUTATIONS; LANDSCAPE; MULTIMERS; EPITOPES; DESIGN;
D O I
10.1200/JCO.2012.47.7521
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:E439 / E442
页数:4
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