High marks for GWAS

被引：23

作者：

Chanock, Stephen ^{[1
]}

机构：

[1] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA

来源：

NATURE GENETICS | 2009年 / 41卷 / 07期

关键词：

ETIOLOGY; DISEASE; CANCER; RISK;

D O I：

10.1038/ng0709-765

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Two genome-wide association studies for testicular cancer report associations at three new loci, including two candidate genes previously implicated in testicular development, KITLG (ligand for the receptor tyrosine kinase) and SPRY4 (sprouty 4). These studies are notable for the high effect sizes detected and the biological plausibility of the candidate genes.

引用

页码：765 / 766

页数：2

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