Superoxide and nitric oxide: Consequences of varying rates of production and consumption: A theoretical treatment

被引：43

作者：

Liochev, SI ^{[1
]}

Fridovich, I ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USA

来源：

FREE RADICAL BIOLOGY AND MEDICINE | 2002年 / 33卷 / 01期

关键词：

free radicals; hydrogen peroxide; effects of SOD on peroxynitrite; effects of SOD on nitric oxide; effects of SOD on superoxide dismutase; effects on NO; ONOO-; and H2O2;

D O I：

10.1016/S0891-5849(02)00864-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Simple algebraic manipulations and steady state assumptions have been applied to the elucidation of the effects of superoxide dismutase (SOD) on [NO] and [O-2(-)] and on the rates of production of H2O2 and of ONOO-. The deductions help explain seemingly discordant published results and predictions. (C) 2002 Elsevier Science Inc.

引用

页码：137 / 141

页数：5

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