Micro- and nano-motors for biomedical applications

被引:222
作者
Abdelmohsen, Loai K. E. A. [1 ]
Peng, Fei [1 ]
Tu, Yingfeng [1 ]
Wilson, Daniela A. [1 ]
机构
[1] Radboud Univ Nijmegen, Inst Mol & Mat, NL-6525 AJ Nijmegen, Netherlands
基金
欧洲研究理事会;
关键词
CATALYTIC TUBULAR MICROENGINES; AUTONOMOUS MOVEMENT; HYDROGEN-PEROXIDE; CARGO TRANSPORT; MAGNETOTACTIC BACTERIA; CONTROLLED PROPULSION; CHEMICAL LOCOMOTION; DRUG-DELIVERY; NANOMOTORS; MOTION;
D O I
10.1039/c3tb21451f
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
082905 [生物质能源与材料]; 100103 [病原生物学];
摘要
Micro- and nano-motors are a class of miniaturized man-made machines that are able to convert chemical or external energy into mechanical motion. The past decade has witnessed significant progress in the design and fabrication of micro- and nano-motors as a future intelligent and comprehensive biomedical platform. In this review we will critically assess the challenges and limitations of micro- and nanomotors, their mechanism of propulsion and applications in the biomedical field. Important insights into the future development and direction of nano-motors for improved biocompatibility and design will be discussed.
引用
收藏
页码:2395 / 2408
页数:14
相关论文
共 103 条
[1]
A molecular elevator [J].
Badjic, JD ;
Balzani, V ;
Credi, A ;
Silvi, S ;
Stoddart, JF .
SCIENCE, 2004, 303 (5665) :1845-1849
[2]
Micromachine-Enabled Capture and Isolation of Cancer Cells in Complex Media [J].
Balasubramanian, Shankar ;
Kagan, Daniel ;
Hu, Che-Ming Jack ;
Campuzano, Susana ;
Lobo-Castanon, M. Jesus ;
Lim, Nicole ;
Kang, Dae Y. ;
Zimmerman, Maria ;
Zhang, Liangfang ;
Wang, Joseph .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (18) :4161-4164
[3]
BERG HC, 1972, NATURE, V239, P500, DOI 10.1038/239500a0
[4]
MAGNETOTACTIC BACTERIA [J].
BLAKEMORE, R .
SCIENCE, 1975, 190 (4212) :377-379
[5]
Making molecular machines work [J].
Browne, Wesley R. ;
Feringa, Ben L. .
NATURE NANOTECHNOLOGY, 2006, 1 (01) :25-35
[6]
Synthetic nanomotors in microchannel networks: Directional microchip motion and controlled manipulation of cargo [J].
Burdick, Jared ;
Laocharoensuk, Rawiwan ;
Wheat, Philip M. ;
Posner, Jonathan D. ;
Wang, Joseph .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (26) :8164-+
[7]
Propulsion of nanowire diodes [J].
Calvo-Marzal, Percy ;
Sattayasamitsathit, Sirilak ;
Balasubramanian, Shankar ;
Windmiller, Joshua R. ;
Dao, Cuong ;
Wang, Joseph .
CHEMICAL COMMUNICATIONS, 2010, 46 (10) :1623-1624
[8]
Motion-driven sensing and biosensing using electrochemically propelled nanomotors [J].
Campuzano, S. ;
Kagan, D. ;
Orozco, J. ;
Wang, J. .
ANALYST, 2011, 136 (22) :4621-4630
[9]
Bacterial Isolation by Lectin-Modified Microengines [J].
Campuzano, Susana ;
Orozco, Jahir ;
Kagan, Daniel ;
Guix, Maria ;
Gao, Wei ;
Sattayasamitsathit, Sirilak ;
Claussen, Jonathan C. ;
Merkoci, Arben ;
Wang, Joseph .
NANO LETTERS, 2012, 12 (01) :396-401
[10]
Remotely powered self-propelling particles and micropumps based on miniature diodes [J].
Chang, Suk Tai ;
Paunov, Vesselin N. ;
Petsev, Dimiter N. ;
Velev, Orlin D. .
NATURE MATERIALS, 2007, 6 (03) :235-240