Monolithic silica columns for high-efficiency chromatographic separations

被引:474
作者
Tanaka, N [1 ]
Kobayashi, H
Ishizuka, N
Minakuchi, H
Nakanishi, K
Hosoya, K
Ikegami, T
机构
[1] Kyoto Inst Technol, Dept Polymer Sci & Engn, Sakyo Ku, Kyoto 6068585, Japan
[2] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Sakyo Ku, Kyoto 6068501, Japan
关键词
reviews; monolithic silica columns; stationary phases; LC; columns;
D O I
10.1016/S0021-9673(01)01582-5
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Studies on the structural and chromatographic properties of monolithic silica columns were reviewed. Monolithic silica columns prepared from tetraalkoxysilane by a sol-gel method showed high efficiency and high permeability on the basis of the small-sized silica skeletons, large-sized through-pores, and resulting through-pore size/skeleton size ratios much larger than those found in a particle-packed column. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:35 / 49
页数:15
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