Paper Microfluidics Goes Digital

被引:116
作者
Fobel, Ryan [1 ]
Kirby, Andrea E. [2 ]
Ng, Alphonsus H. C. [1 ]
Farnood, Ramin R. [3 ]
Wheeler, Aaron R. [1 ,2 ]
机构
[1] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3E1, Canada
[2] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada
[3] Univ Toronto, Dept Chem Engn & Appl Chem, Toronto, ON M5S 3E5, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
digital microfluidics; paper; diagnostics; enzyme-linked immunosorbent assay (ELISA); electrowetting; LAB-ON-PAPER; DEVICES; PLATFORM;
D O I
10.1002/adma.201305168
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The first example of so-called "digital microfluidics" (DMF) implemented on paper by inkjet printing is reported. A sandwich enzyme-linked immunosorbent assay (ELISA) is demonstrated as an example of a complex, multistep protocol that would be difficult to achieve with capillary-driven paper microfluidics. Furthermore, it is shown that paper-based DMF devices have comparable performance to traditional photolithographically patterned DMF devices at a fraction of the cost. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2838 / 2843
页数:6
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