Efficient synthesis of chrysanthemate precursor from chiral p-tolyl β-(trimethylsilyl)ethyl sulfoxide

被引：18

作者：

Nakamura, S ^{[1
]}

Watanabe, Y ^{[1
]}

Toru, T ^{[1
]}

机构：

[1] Nagoya Inst Technol, Dept Appl Chem, Showa Ku, Nagoya, Aichi 4668555, Japan

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 23期

关键词：

D O I：

10.1039/a908649h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of alpha-lithio-beta-silylethyl sulfoxide with ethyl 4-bromo- or 4-chloro-4-methylpent-2-enoate gives the cyclopropanecarboxylate as a single diastereomer which is converted to (1R)-trans-2-formyl-3,3-dimethylcyclopropanecarboxylate in high overall yield.

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页码：3403 / 3404

页数：2

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