Residual dipolar couplings in structure determination of biomolecules

被引：297

作者：

Prestegard, JH

Bougault, CM

Kishore, AI

机构：

[1] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA

[2] Inst Biol Struct, F-38027 Grenoble 01, France

来源：

CHEMICAL REVIEWS | 2004年 / 104卷 / 08期

关键词：

D O I：

10.1021/cr030419i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Since the mid 1990s, the use of residual dipolar couplings (RDCs) in the analysis of biomolecular structure and dynamics has significantly expanded. A review is given of RDCs and related data as they are used today. Advances made to date in alignment techniques, data acquisition techniques, and analysis methods are outlined. Some examples of applications that use these methods are also covered.

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页码：3519 / 3540

页数：22

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