Development of a high resolution beta camera for a direct measurement of positron distribution on brain surface

被引：12

作者：

Yamamoto, S

Seki, C

Kashikura, K

Fujita, H

Matsuda, T

Ban, R

Kanno, I

机构：

[1] SHIMADZU CO LTD,NAKAGYO KU,KYOTO,JAPAN

[2] JRDC,AKITA LAB,SENSHU KUBOTA,AKITA,JAPAN

[3] RES INST BRAIN & BLOOD VESSELS,SENSHU KUBOTA,AKITA,JAPAN

来源：

IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 1997年 / 44卷 / 04期

关键词：

D O I：

10.1109/23.632720

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We, have developed and tested a high resolution beta camera for a direct measurement of positron distribution on the brain surface of animals. The beta camera consists of a thin CaF2(Eu) scintillator, a tapered fiber optic plate (tapered fiber) and a position sensitive photomultiplier tube (PSPMT). The tapered fiber is the key component of the camera We have developed two different sizes of beta cameras. One is 20mm diameter field of view camera for imaging brain surface of cats. The other is 10mm diameter camera for that of rats. Spatial resolutions of the beta camera for cats and rats were 0.8mm FWHM and 0.5mm FWHM, respectively. We demonstrated that developed beta cameras may overcome the limitation of the spatial resolution of positron emission tomography (PET).

引用

收藏

页码：1538 / 1542

页数：5

相关论文

共 11 条

[1] A COMPARISON OF PET DETECTOR MODULES EMPLOYING RECTANGULAR AND ROUND PHOTOMULTIPLIER TUBES [J].

CHERRY, SR ;

TORNAI, MP ;

LEVIN, CS ;

SIEGEL, S ;

HOFFMAN, EJ ;

ANDREACO, MS ;

WILLIAMS, CW .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1995, 42 (04) :1064-1068

[2] Optical fiber readout of scintillator arrays using a multi-channel PMT: A high resolution PET detector for animal imaging [J].

Cherry, SR ;

Shao, YP ;

Siegel, S ;

Silverman, RW ;

Mumcuoglu, E ;

Meadors, K ;

Phelps, ME .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1996, 43 (03) :1932-1937

[3]

IIDA I, 1995, 42 ANN M SNM, P70

[4]

LECOMTE R, 1994, IEEE NSS MIC, P1063

[5] Optimizing light collection from thin scintillators used in a beta-ray camera for surgical use [J].

Levin, CS ;

MacDonald, LR ;

Tornai, MP ;

Hoffman, EJ ;

Park, J .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1996, 43 (03) :2053-2060

[6]

LJUNGGREN K, 1990, J NUCL MED, V31, P2058

[7] IN-VITRO POSITRON EMISSION TOMOGRAPHY (PET) - USE OF POSITRON EMISSION TRACERS IN FUNCTIONAL IMAGING IN LIVING BRAIN-SLICES [J].

MATSUMURA, K ;

BERGSTROM, M ;

ONOE, H ;

TAKECHI, H ;

WESTERBERG, G ;

ANTONI, G ;

BJURLING, P ;

JACOBSON, GB ;

LANGSTROM, B ;

WATANABE, Y .

NEUROSCIENCE RESEARCH, 1995, 22 (02) :219-229

[8] Receptor imaging technique with C-11-labeled receptor ligands in living brain slices: Its application to time-resolved imaging and saturation analysis of benzodiazepine receptor using [C-11]Ro15-1788 [J].

Murata, T ;

Matsumura, K ;

Onoe, H ;

Bergstrom, M ;

Takechi, H ;

Sihver, S ;

Sihver, W ;

Neu, H ;

Andersson, Y ;

Ogren, M ;

Fasth, KJ ;

Langstrom, B ;

Watanabe, Y .

NEUROSCIENCE RESEARCH, 1996, 25 (02) :145-154

[9] Design considerations and initial performance of a 1.2 cm(2) beta imaging intra-operative probe [J].

Tornai, MP ;

MacDonald, LR ;

Levin, CS ;

Siegel, S ;

Hoffman, EJ .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1996, 43 (04) :2326-2335

[10] DEVELOPMENT OF SKIN SURFACE RADIATION DETECTOR SYSTEM TO MONITOR RADIOACTIVITY IN ARTERIAL BLOOD ALONG WITH POSITRON EMISSION TOMOGRAPHY [J].

WATABE, H ;

MIYAKE, M ;

NARITA, Y ;

NAKAMURA, T ;

ITOH, M .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1995, 42 (04) :1455-1459