Gene finding in genetically isolated populations

被引：97

作者：

Heutink, P ^{[1
]}

Oostra, BA ^{[1
]}

机构：

[1] Erasmus MC Rotterdam, Inst Clin Genet, Dept Clin Genet, NL-3000 DR Rotterdam, Netherlands

来源：

HUMAN MOLECULAR GENETICS | 2002年 / 11卷 / 20期

关键词：

D O I：

10.1093/hmg/11.20.2507

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The struggle to identify susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. One approach that has gained considerable interest is to focus on genetically isolated populations rather than on the general population. There remains much controversy and theoretical debate over the feasibility and advantages of such populations, but recent results speak in favor of the feasibility of this approach, and will be reviewed here.

引用

页码：2507 / 2515

页数：9

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