Solubility of phenylacetic acid, p-hydroxyphenylacetic acid, p-aminophenylacetic acid, p-hydroxybenzoic acid, and ibuprofen in pure solvents

被引：109

作者：

Gracin, S ^{[1
]}

Rasmuson, ÅC ^{[1
]}

机构：

[1] Royal Inst Technol, Dept Chem Engn & Technol, SE-10044 Stockholm, Sweden

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2002年 / 47卷 / 06期

关键词：

D O I：

10.1021/je0255170

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The solubility of phenyl acetic acid, p-hydroxyphenylacetic acid, p-aminophenylacetic acid, p-hydroxybenzoic acid, and ibuprofen in water and in a range of organic solvents of relevance to industrial processing is reported. The solvents used are water, methanol, ethanol, 2-propanol, acetone, 4-methyl-2-pentanone, ethyl acetate, chloroform, and toluene. Solubility data are discussed from the standpoint of molecular aspects of solute-solvent interactions and by estimated solid-phase activity.

引用

页码：1379 / 1383

页数：5

共 4 条

[1]

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[4] Solubility of paracetamol in binary and ternary mixtures of water plus acetone plus toluene [J].

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JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2000, 45 (03) :478-483

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