A new approach to the synthesis of highly substituted 3-pyrrolin-2-ones

被引:10
作者
Arcadi, Antonio [1 ]
Marinelli, Fabio [1 ]
Rossi, Leucio [1 ]
Verdecchia, Mirella [1 ]
机构
[1] Univ Aquila, Dipartimento Chim Ingn Chim & Mat, I-67100 Laquila, Italy
来源
SYNTHESIS-STUTTGART | 2006年 / 12期
关键词
cyclizations; 3-pyrrolin-2-ones; lactams; propargylamines; palladium;
D O I
10.1055/s-2006-942393
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The base-promoted cyclization of internal N-propargyl-malonamides in the presence of carbonate bases at room temperature or at 80 degrees C affords highly substituted 3-pyrrolin-2-ones in good yields.
引用
收藏
页码:2019 / 2030
页数:12
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