Gold(III)-catalyzed annulation of 2-alkynylanilines: A mild and efficient synthesis of indoles and 3-haloindoles

被引：152

作者：

Arcadi, A ^{[1
]}

Bianchi, G ^{[1
]}

Marinelli, F ^{[1
]}

机构：

[1] Univ LAquila, Dipartimento Chim Ingn Chim & Mat, I-67100 Laquila, Italy

来源：

SYNTHESIS-STUTTGART | 2004年 / 04期

关键词：

2-alkynylanilines; indoles; 5-endo-dig cyclization; gold catalysis; halogenations;

D O I：

10.1055/s-2004-815947

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Gold(III)-catalyzed annulation of 2-alkynylanilines in EtOH or EtOH-water mixtures at room temperature gives indoles derivatives in good yields. One-flask protocol for the gold-catalyzed conversion of 2-alkynylanilines to 3-bromo and 3-iodoindoles is also reported.

引用

收藏

页码：610 / 618

页数：9

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