Proposal of a magnetohyperthermic system: preliminary biological tests

被引：11

作者：

Guedes, MHA

Guedes, MEA

Morais, PC

Da Silva, MF

Santos, TS

Alves, JP

Bertelli, CE

Azevedo, RB

Lacava, ZGM ^{[1
]}

机构：

[1] Univ Brasilia, Inst Ciencias Biol, Dept Genet & Morfol, BR-70910900 Brasilia, DF, Brazil

[2] Univ Brasilia, Inst Fis Nucl Fis Aplicada, BR-70919970 Brasilia, DF, Brazil

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2004年 / 272卷

关键词：

alternating magnetic field; magnetothermocytolysis; genotoxicity; hyperthermia; inflammation;

D O I：

10.1016/j.j,,,.2003.12.709

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Magnetohyperthermia (MHT) has been proposed as an alternative therapy for cancer treatment. In order to perform MHT tests we have developed an apparatus operating at 1 MHz with AC magnetic field of 40 Oe in amplitude. Biological tests were performed after exposing the peritoneum region of mice to the AC field. Significative alterations were observed only when peritoneum was exposed by 10 min. The data allowed to conclude that: (1) the damage induced by the AC field to normal cells is related to the exposure time and (2) the equipment developed is adequate to perform MHT experiments. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：2406 / 2407

页数：2

共 8 条

[1]

BACRI JC, 1997, SCI CLIN APPL MAGN C, P44

[2] Targeting HSP70-induced thermotolerance for design of thermal sensitizers [J].