Database resources of the National Center for Biotechnology Information

被引:382
作者
Wheeler, DL [1 ]
Chappey, C [1 ]
Lash, AE [1 ]
Leipe, DD [1 ]
Madden, TL [1 ]
Schuler, GD [1 ]
Tatusova, TA [1 ]
Rapp, BA [1 ]
机构
[1] Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA
关键词
D O I
10.1093/nar/28.1.10
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval and resources that operate on the data in GenBank and a variety of other biological data made available through NCBI's Web site. NCBI data retrieval resources include Entrez, PubMed, LocusLink and the Taxonomy Browser, Data analysis resources include BLAST, Electronic PCR, OrfFinder, RefSeq, UniGene, Database of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing pages, GeneMap'99, Davis Human-Mouse Homology Map, Cancer Chromosome Aberration Project (CCAP) pages, Entrez Genomes, Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, Cancer Genome Anatomy Project (CGAP) pages, SAGEmap, Online Mendelian Inheritance in Man (OMIM) and the Molecular Modeling Database (MMDB), Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at: http://www.ncbi.nlm.nih.gov.
引用
收藏
页码:10 / 14
页数:5
相关论文
共 22 条
[1]   Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].
Altschul, SF ;
Madden, TL ;
Schaffer, AA ;
Zhang, JH ;
Zhang, Z ;
Miller, W ;
Lipman, DJ .
NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402
[2]  
ALTSCHUL SF, 1990, J MOL BIOL, V215, P403, DOI 10.1006/jmbi.1990.9999
[3]   The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999 [J].
Bairoch, A ;
Apweiler, R .
NUCLEIC ACIDS RESEARCH, 1999, 27 (01) :49-54
[4]   The PIR-International Protein Sequence Database [J].
Barker, WC ;
Garavelli, JS ;
McGarvey, PB ;
Marzec, CR ;
Orcutt, BC ;
Srinivasarao, GY ;
Yeh, LSL ;
Ledley, RS ;
Mewes, HW ;
Pfeiffer, F ;
Tsugita, A ;
Wu, C .
NUCLEIC ACIDS RESEARCH, 1999, 27 (01) :39-43
[5]   GenBank [J].
Benson, DA ;
Karsch-Mizrachi, I ;
Lipman, DJ ;
Ostell, J ;
Rapp, BA ;
Wheeler, DL .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :15-18
[6]   The Protein Data Bank [J].
Berman, HM ;
Westbrook, J ;
Feng, Z ;
Gilliland, G ;
Bhat, TN ;
Weissig, H ;
Shindyalov, IN ;
Bourne, PE .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :235-242
[7]   Human/mouse homology relationships [J].
DeBry, RW ;
Seldin, MF .
GENOMICS, 1996, 33 (03) :337-351
[8]   A physical map of 30,000 human genes [J].
Deloukas, P ;
Schuler, GD ;
Gyapay, G ;
Beasley, EM ;
Soderlund, C ;
Rodriguez-Tomé, P ;
Hui, L ;
Matise, TC ;
McKusick, KB ;
Beckmann, JS ;
Bentolila, S ;
Bihoreau, MT ;
Birren, BB ;
Browne, J ;
Butler, A ;
Castle, AB ;
Chiannilkulchai, N ;
Clee, C ;
Day, PJR ;
Dehejia, A ;
Dibling, T ;
Drouot, N ;
Duprat, S ;
Fizames, C ;
Fox, S ;
Gelling, S ;
Green, L ;
Harrison, P ;
Hocking, R ;
Holloway, E ;
Hunt, S ;
Keil, S ;
Lijnzaad, P ;
Louis-Dit-Sully, C ;
Ma, J ;
Mendis, A ;
Miller, J ;
Morissette, J ;
Muselet, D ;
Nusbaum, HC ;
Peck, A ;
Rozen, S ;
Simon, D ;
Slonim, DK ;
Staples, R ;
Stein, LD ;
Stewart, EA ;
Suchard, MA ;
Thangarajah, T ;
Vega-Czarny, N .
SCIENCE, 1998, 282 (5389) :744-746
[9]   Data management and analysis for gene expression arrays [J].
Ermolaeva, O ;
Rastogi, M ;
Pruitt, KD ;
Schuler, GD ;
Bittner, ML ;
Chen, YD ;
Simon, R ;
Meltzer, P ;
Trent, JM ;
Boguski, MS .
NATURE GENETICS, 1998, 20 (01) :19-23
[10]   Making effective use of human genomic sequence data [J].
Jang, WH ;
Chen, HC ;
Sicotte, H ;
Schuler, GD .
TRENDS IN GENETICS, 1999, 15 (07) :284-286