Use of lnCl3 as a cocatalyst and a Cl2Pd(DPEphos)-P(2-Furyl)3 catalyst system for one-pot hydrometalation-cross-coupling and carbometalation-cross-coupling tandem processes
被引:56
作者:
Qian, MX
论文数: 0引用数: 0
h-index: 0
机构:
Purdue Univ, Hebert C Brown Labs Chem, W Lafayette, IN 47907 USAPurdue Univ, Hebert C Brown Labs Chem, W Lafayette, IN 47907 USA
Qian, MX
[1
]
Huang, ZH
论文数: 0引用数: 0
h-index: 0
机构:
Purdue Univ, Hebert C Brown Labs Chem, W Lafayette, IN 47907 USAPurdue Univ, Hebert C Brown Labs Chem, W Lafayette, IN 47907 USA
Huang, ZH
[1
]
Negishi, E
论文数: 0引用数: 0
h-index: 0
机构:
Purdue Univ, Hebert C Brown Labs Chem, W Lafayette, IN 47907 USAPurdue Univ, Hebert C Brown Labs Chem, W Lafayette, IN 47907 USA
Negishi, E
[1
]
机构:
[1] Purdue Univ, Hebert C Brown Labs Chem, W Lafayette, IN 47907 USA
One-pot conversion of alkynes to regio- and stereodefined alkenylmetals containing Al and Zr via hydrometalation or carbometalation followed by their Pd-catalyzed cross-coupling with (E)-ICH=CHBr or (E)-ICH=CHCl proceeds cleanly and selectively to give the corresponding 1-halo-1,3-dienes in excellent yields using a catalyst system consisting Of Cl2Pd(DPEphos), DIBAL-H, and TFP (catalyst A) with InCl3 as a cocatalyst.