Mouse genome database 2016

被引：64

作者：

Bult, Carol J. ^{[1
]}

Eppig, Janan T. ^{[1
]}

Blake, Judith A. ^{[1
]}

Kadin, James A. ^{[1
]}

Richardson, Joel E. ^{[1
]}

机构：

[1] Jackson Lab, 600 Main St, Bar Harbor, ME 04609 USA

来源：

NUCLEIC ACIDS RESEARCH | 2016年 / 44卷 / D1期

关键词：

GENE-FUNCTION; GENERATION; RESOURCE; BIOLOGY; INTEGRATION; WAREHOUSE;

D O I：

10.1093/nar/gkv1211

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data.

引用

页码：D840 / D847

页数：8

共 36 条

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