Ordered recruitment: Gene-specific mechanism of transcription activation

被引:205
作者
Cosma, MP [1 ]
机构
[1] Telethon Inst Genet & Med, I-80131 Naples, Italy
关键词
D O I
10.1016/S1097-2765(02)00604-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Activators, chromatin-modifying enzymes, and basal transcription factors unite to activate genes, but are recruited in a precise order to promoters. The timing of the activation of transcription and the ordered recruitment of factors to promoters are the engines which, at the right moment and for the right length of time, drive the transcriptional regulation of each gene throughout the life of a cell.
引用
收藏
页码:227 / 236
页数:10
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