A CO2- and temperature-switchable "schizophrenic" block copolymer: from vesicles to micelles

被引：113

作者：

Feng, Anchao ^{[1
]}

Zhan, Chengbo ^{[1
]}

Yan, Qiang ^{[1
]}

Liu, Bowen ^{[1
]}

Yuan, Jinying ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 64期

基金：

中国国家自然科学基金;

关键词：

LIVING RADICAL POLYMERIZATION; DIBLOCK COPOLYMER; MEMBRANE-PERMEABILITY; HYBRID NANOPARTICLES; RAFT POLYMERIZATION; REVERSE MICELLES; AQUEOUS-SOLUTION; DRUG-DELIVERY; STIMULI; PH;

D O I：

10.1039/c4cc03156c

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

CO2-responsiveness is imported into amphiphilic block copolymers, poly[(N,N-diethylaminoethyl methacrylate)-b-(N-isopropylactylamide)] (PDEAEMA-b-PNIPAM), and a system dual-responsive to CO2 and temperature is constructed. The copolymer self-assembles in aqueous solution, and undergoes phase transition when CO2 and temperature stimuli occur, since the stimuli give rise to the conversion of the hydrophilicity of both blocks. Combining CO2 and temperature as triggers, schizophrenic micelle to vesicle morphological transition of the polymer assemblies is controlled.

引用

收藏

页码：8958 / 8961

页数：4

相关论文

共 51 条

[1]

Unusual aggregation behavior of a novel tertiary amine methacrylate-based diblock copolymer: Formation of micelles and reverse micelles in aqueous solution [J].

Butun, V ;

Billingham, NC ;

Armes, SP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (45) :11818-11819

[2]

Living free-radical polymerization by reversible addition-fragmentation chain transfer: The RAFT process [J].

Chiefari, J ;

Chong, YK ;

Ercole, F ;

Krstina, J ;

Jeffery, J ;

Le, TPT ;

Mayadunne, RTA ;

Meijs, GF ;

Moad, CL ;

Moad, G ;

Rizzardo, E ;

Thang, SH .

MACROMOLECULES, 1998, 31 (16) :5559-5562

[3]

Polymersomes [J].

Discher, Dennis E. ;

Ahmed, Fariyal .

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 2006, 8 :323-341

[4]

Self-Assembly of Hydrophilic Homopolymers: A Matter of RAFT End Groups [J].

Du, Jianzhong ;

Willcock, Helen ;

Patterson, Joseph P. ;

Portman, Ian ;

O'Reilly, Rachel K. .

SMALL, 2011, 7 (14) :2070-2080

[5]

pH-Responsive Vesicles from a Schizophrenic Diblock Copolymer [J].

Du, Jianzhong ;

O'Reilly, Rachel K. .

MACROMOLECULAR CHEMISTRY AND PHYSICS, 2010, 211 (14) :1530-1537

[6]

Smart Nanocontainers: Progress on Novel Stimuli-Responsive Polymer Vesicles [J].

Feng, Anchao ;

Yuan, Jinying .

MACROMOLECULAR RAPID COMMUNICATIONS, 2014, 35 (08) :767-779

[7]

Feng AC, 2012, PROG CHEM, V24, P1995

[8]

Well-defined graft copolymers: from controlled synthesis to multipurpose applications [J].

Feng, Chun ;

Li, Yongjun ;

Yang, Dong ;

Hu, Jianhua ;

Zhang, Xiaohuan ;

Huang, Xiaoyu .

CHEMICAL SOCIETY REVIEWS, 2011, 40 (03) :1282-1295

[9]

Synthetic Bio-nanoreactor: Mechanical and Chemical Control of Polymersome Membrane Permeability [J].

Gaitzsch, Jens ;

Appelhans, Dietmar ;

Wang, Linge ;

Battaglia, Giuseppe ;

Voit, Brigitte .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (18) :4448-4451

[10]

Hybrid nanoparticles with CO2-responsive shells and fluorescence-labelled magnetic cores [J].

Guo, Jun ;

Wang, Niejun ;

Wu, Jingjun ;

Ye, Qiquan ;

Zhang, Chong ;

Xing, Xin-Hui ;

Yuan, Jinying .

JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2 (04) :437-442

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