APCs size up antigens

被引：3

作者：

Bahjat, KS ^{[1
]}

Schoenberger, SP ^{[1
]}

机构：

[1] La Jolla Inst Allergy & Immunol, Div Cellular Immunol, San Diego, CA 92121 USA

来源：

NATURE MEDICINE | 2004年 / 10卷 / 07期

关键词：

D O I：

10.1038/nm0704-679

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Intracellular antigens - from viruses, tumors, bacteria and other sources - pose a challenge to the immune response and to vaccine development. How do such antigens enter antigen-presenting cells? Three new studies examine this process, implicating whole proteins instead of small peptides as key intermediaries.

引用

页码：679 / 681

页数：4

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