A T2504A mutation in the 23S rRNA gene responsible for high-level resistance to linezolid of Staphylococcus epidermidis

被引:30
作者
Liakopoulos, Apostolos [1 ,2 ,3 ]
Neocleous, Charalambos [1 ,2 ]
Klapsa, Dimitra [1 ,2 ]
Kanellopoulou, Maria [4 ]
Spiliopoulou, Iris [5 ]
Mathiopoulos, Kostas D. [3 ]
Papafrangas, Evangelos [4 ]
Petinaki, Efi [1 ,2 ]
机构
[1] Univ Thessalia, Sch Med, Dept Microbiol, Larisa, Greece
[2] Inst BioMed Res & Technol, Dept Mol Microbiol, Larisa, Greece
[3] Univ Thessalia, Dept Biochem & Biotechnol, Larisa, Greece
[4] Sismanogl Gen Hosp Athens, Dept Microbiol, Athens, Greece
[5] Univ Patras, Sch Med, Dept Microbiol, GR-26110 Patras, Greece
关键词
S; epidermidis; staphylococci; oxazolidinones; AUREUS;
D O I
10.1093/jac/dkp167
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
引用
收藏
页码:206 / 207
页数:2
相关论文
共 6 条
[1]  
[Anonymous], 2006, METH DIL ANT SUSC TE, Vseventh
[2]   In vitro activity of the oxazolidinone RWJ-416457 against linezolid-resistant and -susceptible staphylococci and enterococci [J].
Livermore, David M. ;
Warner, Marina ;
Mushtaq, Shazad ;
North, Sarah ;
Woodford, Neil .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (03) :1112-1114
[3]   Linezolid resistance in sequential Staphylococcus aureus isolates associated with a T2500A mutation in the 23S rRNA gene and loss of a single copy of rRNA [J].
Meka, VG ;
Pillai, SK ;
Sakoulas, G ;
Wennersten, C ;
Venkataraman, L ;
DeGirolami, PC ;
Eliopoulos, GM ;
Moellering, RC ;
Gold, HS .
JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (02) :311-317
[4]   First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States [J].
Mendes, Rodrigo E. ;
Deshpande, Lalitagauri M. ;
Castanheira, Mariana ;
DiPersio, Joseph ;
Saubolle, Michael A. ;
Jones, Ronald N. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (06) :2244-2246
[5]   Mutation of L4 ribosomal protein conferring unusual macrolide resistance in two independent clinical isolates of Staphylococcus aureus [J].
Prunier, AL ;
Trong, HN ;
Tande, D ;
Segond, C ;
Leclercq, R .
MICROBIAL DRUG RESISTANCE, 2005, 11 (01) :18-20
[6]   Linezolid resistance in a clinical isolate of Staphylococcus aureus [J].
Tsiodras, S ;
Gold, HS ;
Sakoulas, G ;
Eliopoulos, GM ;
Wennersten, C ;
Venkataraman, L ;
Moellering, RC ;
Ferraro, MJ .
LANCET, 2001, 358 (9277) :207-208