Side effects may include evolution

被引：10

作者：

Cirz, Ryan T. ^{[1
]}

Gingles, Neill ^{[1
]}

Romesberg, Floyd E. ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

来源：

NATURE MEDICINE | 2006年 / 12卷 / 08期

关键词：

D O I：

10.1038/nm0806-890

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Certain antibiotics prompt Streptococcus pneumoniae to take up DNA from the environment, which may enable the microbe to acquire genes for antibiotic resistance.

引用

页码：890 / 891

页数：3

共 15 条

[1] SOS response promotes horizontal dissemination of antibiotic resistance genes [J].

Beaber, JW ;

Hochhut, B ;

Waldor, MK .

NATURE, 2004, 427 (6969) :72-74

[2] Inhibition of mutation and combating the evolution of antibiotic resistance [J].

Cirz, RT ;

Chin, JK ;

Andes, DR ;

de Crécy-Lagard, V ;

Craig, WA ;

Romesberg, FE .

PLOS BIOLOGY, 2005, 3 (06) :1024-1033

[3] Induction of competence regulons as a general response to stress in gram-positive bacteria [J].

Claverys, Jean-Pierre ;

Prudhomme, Marc ;

Martin, Bernard .

ANNUAL REVIEW OF MICROBIOLOGY, 2006, 60 :451-475

[4] Ciprofloxacin and trimethoprim cause phage induction and virulence modulation in Staphylococcus aureus [J].

Goerke, C ;

Köller, J ;

Wolz, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (01) :171-177

[5] BACTERIAL GENE-TRANSFER BY NATURAL GENETIC-TRANSFORMATION IN THE ENVIRONMENT [J].

LORENZ, MG ;

WACKERNAGEL, W .

MICROBIOLOGICAL REVIEWS, 1994, 58 (03) :563-602

[6] β-lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus [J].

Maiques, E ;

Ubeda, C ;

Campoy, S ;

Salvador, N ;

Lasa, I ;

Novick, RP ;

Barbé, J ;

Penadés, JR .

JOURNAL OF BACTERIOLOGY, 2006, 188 (07) :2726-2729

[7] The SOS response regulates adaptive mutation [J].

McKenzie, GJ ;

Harris, RS ;

Lee, PL ;

Rosenberg, SM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (12) :6646-6651

[8] An operon that confers UV resistance by evoking the SOS mutagenic response in streptococcal conjugative transposon Tn5252 [J].

Munoz-Najar, U ;

Vijayakumar, MN .

JOURNAL OF BACTERIOLOGY, 1999, 181 (09) :2782-2788

[9] Antibiotic stress induces genetic transformability in the human pathogen Streptococcus pneumoniae [J].

Prudhomme, Marc ;

Attaiech, Laetitia ;

Sanchez, Guillaume ;

Martin, Bernard ;

Claverys, Jean-Pierre .

SCIENCE, 2006, 313 (5783) :89-92

[10]

Rattray AJ, 2002, GENETICS, V162, P1063

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