Immunostimulating agents: What next? A review of their present and potential medical applications

被引：64

作者：

Werner, GH ^{[1
]}

Jolles, P ^{[1
]}

机构：

[1] MUSEUM NATL HIST NAT, CNRS, URA 401, LAB CHIM SUBST NAT, F-75231 PARIS, FRANCE

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1996年 / 242卷 / 01期

关键词：

immunopharmacology; immunostimulant; immunomodulator; adjuvant; biological response modifier;

D O I：

10.1111/j.1432-1033.1996.0001r.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many chemical entities, either from natural sources or prepared by synthesis, are known to exert stimulating activities on various functions of the immune system, such as antibody production, resistance to infections, rejection of malignant cells, etc. In this review, the origin, chemical structures and main activities of several immunostimulants are described, with special emphasis on their present or potential medical usefulness. An attempt is made to envisage the future of this type of pharmacological agents, excluding however from the presentation the endogenous modulators of the immune system (cytokines), the production and activities of which are influenced by the immunostimulants themselves.

引用

页码：1 / 19

页数：19

共 156 条

[21]

BORGHI MO, 1994, INT J IMMUNOTHER, V10, P35

[22]

BRAGA PC, 1994, J CHEMOTHERAPY, V6, P354

[23]

BRAKENHOFF JPJ, 1995, DIG NEUROL PSYCH, V8, P397

[24] ENDOTOXIN PRETREATMENT INCREASES ENDOGENOUS MYOCARDIAL CATALASE ACTIVITY AND DECREASES ISCHEMIA REPERFUSION INJURY OF ISOLATED RAT HEARTS [J].

BROWN, JM ;

GROSSO, MA ;

TERADA, LS ;

WHITMAN, GJR ;

BANERJEE, A ;

WHITE, CW ;

HARKEN, AH ;

REPINE, JE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (07) :2516-2520

[25]

CAPSONI F, 1991, J CHEMOTHER S3, V3, P147

[26]

CAREDDU P, 1992, ADV THER, V9, P174

[27] ISOLATION AND CHARACTERIZATION OF IMMUNOSTIMULATIVE PEPTIDES FROM SOYBEAN [J].

CHEN, JR ;

SUETSUNA, K ;

YAMAUCHI, F .

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 1995, 6 (06) :310-313

[28]

CHEN R, 1994, NUCLEOS NUCLEOT, V131, P551

[29]

CHIHARA G, 1984, EOS-RIV IMMUNOL, V4, P85

[30]

CHIRIGOS MA, 1992, THYMUS, V19, pS7

← 1 2 3 4 5 6 7 8 9 10 →