Erythroid development in the mammalian embryo

被引：36

作者：

Baron, Margaret H. ^{[1
,2
,3
,4
,5
,6
]}

Vacaru, Andrei ^{[1
,4
]}

Nieves, Johnathan ^{[1
,4
]}

机构：

[1] Icahn Sch Med Mt Sinai, Dept Med, New York, NY 10029 USA

[2] Icahn Sch Med Mt Sinai, Dept Dev & Regenerat Biol, New York, NY 10029 USA

[3] Icahn Sch Med Mt Sinai, Dept Oncol Sci, New York, NY 10029 USA

[4] Icahn Sch Med Mt Sinai, Dept Tisch Canc Inst, New York, NY 10029 USA

[5] Icahn Sch Med Mt Sinai, Black Family Stem Cell Inst, New York, NY 10029 USA

[6] Icahn Sch Med Mt Sinai, Grad Sch Biomed Sci, New York, NY 10029 USA

来源：

BLOOD CELLS MOLECULES AND DISEASES | 2013年 / 51卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Primitive erythropoiesis; Transgenic mice; Mammalian embryo; Yolk sac; Fetal liver; Erythroid differentiation; HEMATOPOIETIC STEM-CELLS; YOLK-SAC HEMATOPOIESIS; GENOME-WIDE ANALYSIS; RED-BLOOD-CELLS; PRIMITIVE ERYTHROPOIESIS; MICE LACKING; FETAL LIVER; IN-VIVO; COMPARATIVE RHEOLOGY; GENE-EXPRESSION;

D O I：

10.1016/j.bcmd.2013.07.006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Erythropoiesis is the process by which progenitors for red blood cells are produced and terminally differentiate. In all vertebrates, two morphologically distinct erythroid lineages (primitive, embryonic, and definitive, fetal/adult) form successively within the yolk sac, fetal liver, and marrow and are essential for normal development. Red blood cells have evolved highly specialized functions in oxygen transport, defense against oxidation, and vascular remodeling. Here we review key features of the ontogeny of red blood cell development in mammals, highlight similarities and differences revealed by genetic and gene expression profiling studies, and discuss methods for identifying erythroid cells at different stages of development and differentiation. (C) 2013 Elsevier Inc All rights reserved.

引用

页码：213 / 219

页数：7

共 115 条

[61] A robust and high-throughput Cre reporting and characterization system for the whole mouse brain [J].

Madisen, Linda ;

Zwingman, Theresa A. ;

Sunkin, Susan M. ;

Oh, Seung Wook ;

Zariwala, Hatim A. ;

Gu, Hong ;

Ng, Lydia L. ;

Palmiter, Richard D. ;

Hawrylycz, Michael J. ;

Jones, Allan R. ;

Lein, Ed S. ;

Zeng, Hongkui .

NATURE NEUROSCIENCE, 2010, 13 (01) :133-U311

[62] FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors [J].

Mancini, Elena ;

Sanjuan-Pla, Alejandra ;

Luciani, Luisa ;

Moore, Susan ;

Grover, Amit ;

Zay, Agnes ;

Rasmussen, Kasper D. ;

Luc, Sidinh ;

Bilbao, Daniel ;

O'Carroll, Donal ;

Jacobsen, Sten Eirik ;

Nerlov, Claus .

EMBO JOURNAL, 2012, 31 (02) :351-365

[63] Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6 [J].

Matsumoto, N ;

Kubo, A ;

Liu, HX ;

Akita, K ;

Laub, F ;

Ramirez, F ;

Keller, G ;

Friedman, SL .

BLOOD, 2006, 107 (04) :1357-1365

[64] Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus [J].

McGrath, Kathleen E. ;

Kingsley, Paul D. ;

Koniski, Anne D. ;

Porter, Rebecca L. ;

Bushnell, Timothy P. ;

Palis, James .

BLOOD, 2008, 111 (04) :2409-2417

[65] A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo [J].

McGrath, Kathleen E. ;

Frame, Jenna M. ;

Fromm, George J. ;

Koniski, Anne D. ;

Kingsley, Paul D. ;

Little, Jane ;

Bulger, Michael ;

Palis, James .

BLOOD, 2011, 117 (17) :4600-4608

[66] Circulation is established in a stepwise pattern in the mammalian embryo [J].

McGrath, KE ;

Koniski, AD ;

Malik, J ;

Palis, J .

BLOOD, 2003, 101 (05) :1669-1676

[67] Global gene expression analysis of human erythroid progenitors [J].

Merryweather-Clarke, Alison T. ;

Atzberger, Ann ;

Soneji, Shamit ;

Gray, Nicki ;

Clark, Kevin ;

Waugh, Craig ;

McGowan, Simon J. ;

Taylor, Stephen ;

Nandi, Asoke K. ;

Wood, William G. ;

Roberts, David J. ;

Higgs, Douglas R. ;

Buckle, Veronica J. ;

Robson, Kathryn J. H. .

BLOOD, 2011, 117 (13) :E96-E108

[68] NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development [J].

Miccio, Annarita ;

Wang, Yuhuan ;

Hong, Wei ;

Gregory, Gregory D. ;

Wang, Hongxin ;

Yu, Xiang ;

Choi, John K. ;

Shelat, Suresh ;

Tong, Wei ;

Poncz, Mortimer ;

Blobel, Gerd A. .

EMBO JOURNAL, 2010, 29 (02) :442-456

[69] Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation [J].

Mukhopadhyay, M ;

Teufel, A ;

Yamashita, T ;

Agulnick, AD ;

Chen, L ;

Downs, KM ;

Schindler, A ;

Grinberg, A ;

Huang, SP ;

Dorward, D ;

Westphal, H .

DEVELOPMENT, 2003, 130 (03) :495-505

[70] Genome-wide analysis shows that Ldb1 controls essential hematopoietic genes/pathways in mouse early development and reveals novel players in hematopoiesis [J].

Mylona, Athina ;

Andrieu-Soler, Charlotte ;

Thongjuea, Supat ;

Martella, Andrea ;

Soler, Eric ;

Jorna, Ruud ;

Hou, Jun ;

Kockx, Christel ;

van Ijcken, Wilfred ;

Lenhard, Boris ;

Grosveld, Frank .

BLOOD, 2013, 121 (15) :2902-2913

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